Comments on: Vinblastine http://totallysynthetic.com/blog/?p=805 4,512 Ph. D. students died to make this blog... Thu, 09 Sep 2010 08:39:52 -0600 hourly 1 http://wordpress.org/?v=3.0 By: TotallySynthetic.com » Blog Archive » Fendleridine http://totallysynthetic.com/blog/?p=805&cpage=1#comment-290656 TotallySynthetic.com » Blog Archive » Fendleridine Sun, 21 Mar 2010 11:19:43 +0000 http://totallysynthetic.com/blog/?p=805#comment-290656 [...] back-to-back from one group!  This target has clearly developed from their work in vindoline and vinblastine, using similar synthetic techniques.  Their interest in this target in particular was to assign [...] [...] back-to-back from one group!  This target has clearly developed from their work in vindoline and vinblastine, using similar synthetic techniques.  Their interest in this target in particular was to assign [...]

]]> By: Fendleridine « Porterlab's Blog http://totallysynthetic.com/blog/?p=805&cpage=1#comment-285621 Fendleridine « Porterlab's Blog Tue, 02 Mar 2010 16:40:16 +0000 http://totallysynthetic.com/blog/?p=805#comment-285621 [...] back-to-back from one group!  This target has clearly developed from their work in vindoline and vinblastine, using similar synthetic techniques.  Their interest in this target in particular was to assign [...] [...] back-to-back from one group!  This target has clearly developed from their work in vindoline and vinblastine, using similar synthetic techniques.  Their interest in this target in particular was to assign [...]

]]> By: kookimebux http://totallysynthetic.com/blog/?p=805&cpage=1#comment-200860 kookimebux Sun, 01 Feb 2009 18:54:09 +0000 http://totallysynthetic.com/blog/?p=805#comment-200860 Hello. And Bye. :) Hello. And Bye. :)

]]> By: Dude http://totallysynthetic.com/blog/?p=805&cpage=1#comment-89801 Dude Wed, 05 Mar 2008 12:50:07 +0000 http://totallysynthetic.com/blog/?p=805#comment-89801 Nassima - you are a fricking twit. Nassima – you are a fricking twit.

]]> By: Tot. Syn. http://totallysynthetic.com/blog/?p=805&cpage=1#comment-89564 Tot. Syn. Tue, 04 Mar 2008 17:26:11 +0000 http://totallysynthetic.com/blog/?p=805#comment-89564 Why would I have it?!! Why don't you look in the supporting information for a synthesis of Minovine... like here: http://pubs.acs.org/subscribe/journals/jacsat/suppinfo/ja061256t/ja061256tsi20060614_073759.pdf Why would I have it?!! Why don’t you look in the supporting information for a synthesis of Minovine… like here:
http://pubs.acs.org/subscribe/journals/jacsat/suppinfo/ja061256t/ja061256tsi20060614_073759.pdf

]]> By: nassima http://totallysynthetic.com/blog/?p=805&cpage=1#comment-89513 nassima Tue, 04 Mar 2008 13:20:42 +0000 http://totallysynthetic.com/blog/?p=805#comment-89513 can you send to me the specter RMN of alkaloids minovine and vincadifformine with here etalements if you want because i need him in near time Please help me in this research Thank you can you send to me the specter RMN of alkaloids minovine and vincadifformine with here etalements
if you want because i need him in near time

Please help me in this research

Thank you

]]> By: ChemSpider Blog » Blog Archive » We Need for an InChIKey Resolver and We Need It Now http://totallysynthetic.com/blog/?p=805&cpage=1#comment-82020 ChemSpider Blog » Blog Archive » We Need for an InChIKey Resolver and We Need It Now Fri, 08 Feb 2008 17:14:11 +0000 http://totallysynthetic.com/blog/?p=805#comment-82020 [...] on ChemSpider and that’s nice to see but we started there so that’s irrelevant really. I also see a link to a TotallySynthetic.com blog posting. Excellent. Clicking on the link I open the page and there it is. Vinblastine. Nice. Oh, and a list [...] [...] on ChemSpider and that’s nice to see but we started there so that’s irrelevant really. I also see a link to a TotallySynthetic.com blog posting. Excellent. Clicking on the link I open the page and there it is. Vinblastine. Nice. Oh, and a list [...]

]]> By: oxone http://totallysynthetic.com/blog/?p=805&cpage=1#comment-63766 oxone Tue, 23 Oct 2007 19:51:08 +0000 http://totallysynthetic.com/blog/?p=805#comment-63766 The reaction shown here (right after the smily) is incorrect. Instead of H, You attached methyl on the center bottom. Check it. The reaction shown here (right after the smily) is incorrect.
Instead of H, You attached methyl on the center bottom. Check it.

]]> By: Stella Kro http://totallysynthetic.com/blog/?p=805&cpage=1#comment-63579 Stella Kro Mon, 22 Oct 2007 01:39:33 +0000 http://totallysynthetic.com/blog/?p=805#comment-63579 No applying interest for this natural product. Vinka alkaloïds, Vinblastin, are used for many years in anticancer therapy. It is extracted from Madagascar flowers and an hemisynthesis of the drug is prapared cheaply from this material. Total synthesis of this molecule has no interest for the science today. More potent fluorous analogues are already in developpment. It's the same thing with Taxotere prepared from advance natural product, by hemisynthesis. No applying interest for this natural product. Vinka alkaloïds, Vinblastin, are used for many years in anticancer therapy. It is extracted from Madagascar flowers and an hemisynthesis of the drug is prapared cheaply from this material. Total synthesis of this molecule has no interest for the science today. More potent fluorous analogues are already in developpment. It’s the same thing with Taxotere prepared from advance natural product, by hemisynthesis.

]]> By: jimbo http://totallysynthetic.com/blog/?p=805&cpage=1#comment-63563 jimbo Sun, 21 Oct 2007 21:25:11 +0000 http://totallysynthetic.com/blog/?p=805#comment-63563 GYA: clearly. I disagree with you so I must be delusional. GYA: clearly. I disagree with you so I must be delusional.

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