Baran, Seiple, Su, Young, Lewis and Yamaguchi. ACIEE, 2009, EarlyView. DOI: 10.1002/anie.200907112.
Y’know, I was kinda hoping for a bit of break between blog-posts this winter, as the amount of online publications tends to tail-off around the year-end.  However, not only have the publications been thick-’n’-fast (got quite a lot of material to get through), but up pops palau’amine.  I really did think that Angewandte would hold-off until sometime in early 2010, but here it is – and it lives up to Baran’s reputation.  I mean that in …

Ley, Francais, Leyva, Etxebarria-Jardi. Org. Lett., 2009, ASAP. DOI: 10.1021/ol902676t.
For those UKian readers out there, there’s a fittingness to my posting a Cambridge paper following an Oxford last week.  Having spent a bit of time at both, it’s hard for me to pick a particular allegience, but I guess I have to go light blue, and congratulate the boys for their dug-in performance at Twickenham a few weeks back.  But I am particularly lucky to have been at both, as their approach to organic chemistry was so markedly different. …

Davies, Bagal, Lee, Roberts, Russell, Scott, Thomson. Org. Lett., 2009, ASAP. DOI: 10.1021/ol902533b.
More of a post-ette than a full post, this tasty little nugget was found buried amongst effective reposts and updates.  Out there to give you a freaky sense of de ja vous are full papers on kendomycin, spirastrellolide, nakiterpiosin… finding something new was an effort!
What we’ve got here are a pair of closely related synthese of some poly hydroxylated piperidenes; notable for their glycosidase inhibitory effects.  Huh, I hear you say (actually, probably not – there are …

Yeah, I’ve not posted in a bit… Cephalostatin 1 is going into Chemistry World next month, but this months is also worth a read.  Darren Dixon’s synthesis of Nakadomarin A contains quite a few interesting transformation, and is very succinct.

Corey, Brown. Org. Lett., 2009, ASAP. DOI: 10.1021/ol9025793.  . Corey, Behforouz, Ishiguro. JACS., 1979, 101, 1608–1609. DOI: 10.1021/ja00500a048. 
Again, it’s been a while since I blogged, and this time the excuses are two-fold.  First of all, I moved home recently to the leafy London suburb of Surbiton (saaf-wess, for natives…), and have been without my computer, interweb access and beer, all three of which are required for blogging.  However, more critically, there’s been a real dearth of total synthesis in the ASAPs, so much so that this paper isn’t even a formal synthesis (not in the title at …