Home » Still In The RBF

sarain A   

27 March 2006 9,456 views 2 Comments

Sarain-A.jpg

Overman, Garg & Hiebert. ACIE, 2006, EarlyView. DOI: 10.1002/anie.200600417

Rather strange looking beast; two fused macrocycles in a pentacyclic system. The final cyclisation goes via a Stille coupling, using the trans- vinyl stannane and a cis- vinyl iodide. However, more interesting to me was the condensation approach for creation of the eight-member ring in 86%. Nice.

Sarain-A_2.jpg

1 Star2 Stars3 Stars4 Stars5 Stars (No Ratings Yet)
Loading ... Loading ...

2 Comments

  • New reader says:

    Good accomplishment but waaaay to long…

  • mp3 guru says:

    mp3 guru…

    mp3%2Bguru%2B%2B%253Ca%2Bhref%253D%2Bhttp%253A%252F%252Fmp3mamba.com%2B%253Emp3%2Bguru%253C%252Fa%253E%2B%255BURL%253D%2Bhttp%253A%252F%252Fmp3mamba.com%2B%255Dmp3%2Bguru%255B%252FURL%255D%2B%2Binformation%250D%250A%250D%250AExcellent%2Bsite%2B%252D%2B…